Fakhri was born in Queens, New York to a Czech mother and a Pakistani father. Her parents divorced each other when she was barely six or seven years old. Fakhri is a U.S. citizen. When asked about her father's homeland, she revealed that she has never visited Pakistan. Her favourite hobbies include cooking, meditation and yoga. Fakhri appeared on America's Next Top Model Cycles 2 and 3 in 2004. She posed for the 2009 Kingfisher Swimsuit Calendar. In 2011, she made her feature film debut in the Bollywood film, Rockstar, alongside Ranbir Kapoor which was released on November 11, 2011
Fakhri was the first girl to be brought back twice on "America's Next Top Model" (2003) and also the first girl of Pakistani descent in the history of "America's Next Top Model" (2003).